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Exposing "Hemp Derived THC" As New Wave Of Designer Drugs
Designer Drug Pot Disguised As "Natural Hemp Derived" Exposed
Ezekiel 47:12 "And by the river upon the bank thereof, on this side and on that side, shall grow all trees for meat, whose leaf shall not fade, neither shall the fruit thereof be consumed: it shall bring forth new fruit according to his months, because their waters they issued out of the sanctuary: and the fruit thereof shall be for meat, and the leaf thereof for medicine."
Introduction: Because police, and DEA are under the impression that stuff like "thcp", "thca", "delta8", "delta10thc", etc, are "legal", that means authorities are not going to test these products to see what's in them. Lab test can be faked, paid off, or simply leave things out that aren't tested for, which means that they're not worth much. With this in mind, some of these products could have anything in them, from jwh-018, to some other bizarre research chemicals(like jwh-018) or others, that no one has ever heard of. I believe that if a corporation can lie on a label and get away with it, they will. I know for a fact that the hemp industry is hiding proplyene glycol in their products and I have exposed this in the past on 850.NEWS and on the Cannabis page on this blog here on HerbsPedia.org Basically, the new wave of hemp products made legal in 2018 are pharmaceutical versions of fake pot made from CBD isolated from hemp with chemicals and other various means. These products really have nothing to do with hemp for the most part (99%), other than the CBD used to make various forms of THC comes from Hemp. It's actually false marketing to label these legal THC products as "hemp derived" and try to make them look innocent and natural, as they're synthetic. They could have anything in them. I want to see what studies are suggesting about these new designer cannabinoids and I want to distinguish between synthetic drugs and natural drugs, because these are synthetic drugs not natural ones like the socialist want you to believe.
CBD is a PRECURSOR TO VARIOUS FORMS OF THC![7] The "hemp derived" thc products on the market are not extracted from hemp, rather they are synthesized from CBD. I've embedded a video below for intel purposes to prove that you can easily learn how to do this online. I suggest just using real Marijuana but hey, whatever. I would advise against all this chemical crap. I'm trying to expose the fact that this "hemp" industry, is more of a pharmaceutical/chemist industry than an herbalist market. It's less culinary, and more like the works of Albert hofmann. These are pharmaceuticals. Instead of putting the drug in a pill, they've put the drug in gummies, vapes, etc, and make them look healthy, and natural(when they are anything but natural). According to the University Of San Francisco, a drug precursor is: "A chemical or solvent that is used in the manufacture of controlled substances which is regulated by the Drug Enforcement Administration"[8]
I decided to see if I could find academic sources that will show a percentage on the levels of various versions of thc like thcp, thcv, delta8thc, delta10thc, etc to investigate further. I found the results that I was looking for on THCP and here they are: "The inflorescence content of 1 ranged approximately from 0.0023% to 0.0136% (w/w)."[6] These results are in reference to the THCP content of Cannabis sativa sampled in an academic study. This means that there's less than 1% THCP found in Cannabis. This shows that certain compounds in Cannabis(like THCP) remain at very low levels, despite breeding operations taking place over the decades that supposedly increase the plants potency. This is a good argument against the idea that "Marijuana keeps getting stronger." This means that under normal circumstances, there's no way a Cannabis user would be exposed to pharmacologically significant doses of THCP. With this in mind, we can see how using synthetic THCP in doses of anywhere from 5mg to 1000mg is going to have a totally different impact on the mind, and body. We can not take any negative results produced by consumption of a pure synthetic chemical in pharmacologically significant dosages, and then apply those results to the consumption of the dried plant material that has only trace amounts of these same constituents in them. The herb and the gummy are not the same thing.
Not Actually From Hemp: I don't want to come off like a tin foil hat wearing "conspiracy nut", but there's something suspecious going on with these new designer cannabinoids. For one, I find it odd that no one was talking about "thcp" before the legalization of hemp. I had previously read about thcv in a Marijuana book, so I know that some of them are naturally occuring, however these drugs are not being isolated from hemp, as that would be highly un-profitable. These cannabinoids are being manufactured synthetically. You can think of them as the latest in "spice technology". As proof that what I am saying is true, here is a direct quote from the National Library Of Medicine: "Delta-8 THC is one of over 100 cannabinoids produced naturally by the cannabis plant but is not found in significant amounts in the cannabis plant. As a result, concentrated amounts of delta-8 THC are typically manufactured from hemp-derived cannabidiol (CBD)."[9] This is a big deal because where there is drug manufacturing, there's solvents involved, and solvents are highly corosive a lot of the times, and poisonous, and can rot teeth.[x] Here's a thread on reddit where people are talking about how delta8 vapes rot teeth: https://www.reddit.com/r/trees/comments/1e3xiun/is_there_any_safe_way_to_get_high_that_wont_harm/ I can confirm as I have used them as well, that they do rot teeth and slowly induce brain fog over a 1-2 year span before it becomes noticable due to the poisonous proplyene glycol that's added to them, and left over solvents. What the term "manufactured" also means, in regards to your "hemp derived thc" product, is that these products are not natural like you want. They're man-made, rather than God-made, so you can't trust them like you can non-gmo cannabis. I expose on the main Cannabis page of this website how they're putting neurotoxic proplyene glycol in products, and lacing thc with it and then calling it "distillate".
Fake Distillates Warning: Do not use any solidified form of clear looking "distillate" because it is actually proplyene glycol laced with thc. Real distillate isn't a solid, nor does it have the consistency of super glue, nor is it clear. Organic thc is not clear. They are genetically engineering cannabis as well so I hope you know how to breed and are prepared for such emergency situations and already have seeds stocked from years and years ago: (see Dutch Passion blog) A distillate should be an oil, not super-glue like consistency, nor a solid(like hard plastic).
Not The Same: Legal Hemp Derived THC Gummies Are NOT THE SAME AS REAL MARIJUANA EDIBLES. There's never been more anti-marijuana propaghanda being pushed by the socialist. Despite what you're being told all over YouTube and the first page of Google, legal hemp derived thc products are NOT going to produce the same type of high that a real Marijuana edible will, nor will "thca flower"(which also is NOT real Marijuana like the socialist are pushing online). I've had Marijuana edibles way before these Hemp products were even a dream, and real Marijuana edibles are for sure far different despite the fact that your liver converts delta9thc to 11-hydroxy-thc, there's far more to whats happening than that. Marijuana is complex, and hemp products lack the terpenes as well as hundreds of other components that give a real Marijuana edible its almost psychedelic-like high. You won't get that from any legal hemp derived thc products despite what people are saying. They will insist that it's the same and use the fact that your liver converts delta9thc into 11-hydroxy-thc but it still isn't the same. I listen to the experience over what people say.
Why would the socialist lie about that though?: They don't want you to even use real Marijuana in the first place, that's why. They want you to buy delta8 from them, rot your teeth, stay at home, work a crumby slave-labor fortune-500 job, and eat cheese puffs until you're very lazy, and watch TV. They're running a socialist operation to steal the real Marijuana, and replace it with their tainted pharmaceutical version of the drug. Want proof? Look what the DEA, and Police are doing: https://www.dea.gov/press-releases/2018/11/09/la-sheriffs-deputy-two-other-men-arrested-federal-charges-stealing-600, https://www.foxnews.com/us/former-police-officers-sentenced-stealing-thousands-dollars-from-drivers-during-traffic-stops, https://www.cbsnews.com/chicago/news/phoenix-police-officers-indicted-jarrett-snowden-antoine-bell-larry/, https://time.com/3069249/philadelphia-narcotics-cops-charged-with-stealing-drugs-money/, https://www.cbsnews.com/minnesota/news/former-minneapolis-cop-gets-3-years-for-stealing-drugs-during-traffic-stops/, https://www.nbcnews.com/news/us-news/detroit-police-officers-charged-stealing-selling-drugs-n338931, https://www.pbs.org/wgbh/pages/frontline/shows/drugs/archive/copsgobad.html, https://www.nytimes.com/2018/05/08/opinion/police-drugs-warrants.html
Not all "hemp derived cannabinoids" are even natural...: Ever heard of Delta 9o-THC? According to one of the shops selling it, "Delta 9o is the result of combining delta 9 THC with an acetyl group, a process that is commonly used to make drugs and other substances more bioavailable."(secretnature.com). I don't suggest buying from them. Notice the word "combining", and a "process", both of which are indicative of chemical reactions(ie synthesis.) In fact, according to Merriam-Webster's Dictionary, the word "synthesize" means: " 1. to combine or produce by synthesis 2. to make a synthesis of 3. to produce (something, such as music) by an electronic synthesizer"(https://www.merriam-webster.com/dictionary/synthesize) Delta 9o is a synthetic cannabinoid, making it a designer drug, otherwise known as a "research chemical". To me, the labels "synthetic", "research chemical", and "designer drug", all represent the same thing, barely legal pharmaceutical versions of already illegal drugs. THC acetate ester (a.k.a.: THC-O or THCOA) is also NOT natural, as it is synthesized from regular THC.[11] According to one academic source, vaping THC-O may lead to another electronic cigarette or vaping product use-associated lung injury epidemic.[10] According to the Journal Of Analytical Toxicology: "Presented is the analysis of four cannabinoid-based products. These products were part of a case involving visual and auditory hallucinations that precipitated the commission of a felony and subsequent arrest. The products were labeled to contain ∆8-tetrahydrocannabinol (∆8-THC) or THC acetate (THC-O-A). The cannabinoid-based products were determined to contain ∆8-THC, ∆8-THC-O-A, ∆9-THC-O-A and CBD-di-O-A and/or other phytocannabinoids using three different analytical techniques."[13] These findings show that products often contain cannabinoids that are not listed on the label, and that are clearly synthetic and not naturally occuring. There's a real possibility that your "delta9thc" isn't even delta9thc, or is accompanied by other various mutant cannabinoids that were produced via chemical reactions used to make these drugs. According to Virginia Commonwealth University: "The cannabinoid acetate analogs: Δ9-THC-O-acetate (Δ9-THC-O-A), Δ8-THC-O-Acetate (Δ8-THC-O-A), and CBD di-O-acetate (CBD-di-O-A), are classified as Schedule I controlled substances because they do not occur naturally in the cannabis plant and can only be obtained synthetically.Each acetate analog can be synthesized from Δ10-THC, Δ9-THC, and Δ8-THC, and CBD-di-O-A can be synthesized from CBD by an acetic anhydride reaction. This is the same reaction used to synthesize heroin from morphine."[14] This is of concern! "These cannabinoid analogs have caused reason for concern due to their increasing prevalence in gummies and vapes."[14] Here's a news story about the adverse events of these synthetic products: https://www.fox8live.com/2025/06/05/people-report-getting-sick-thcp-edibles-sold-smoke-shops/
More Synthetic/Natural Cannabinoids To Cover: These are basically research chemicals, and they include: HC-H, THC-B, THC- JD, THC-X, HHC-P, and Delta-11 THC.[15] The socialist have the Christians fooled. These drugs are the latest in "spice technology", so to speak. A lot of these only exist in trace amounts in the plant, and are being synthetically manufactured, as previously cited via the National Library Of Medicine. More Cannabinoids for me to research and discuss include: Iso-THC, L-759,656, delta-3-thc, delta-4-thc, delta-7-thc, Abeo-HHC acetate, Cis-THC
THC-B(Δ9-Tetrahydrocannabutol): "THC-B, or Δ9-Tetrahydrocannabutol (Δ9-THCB, THC-B, tetrahydrocannabinol-C4, THC-C4, (C4)-Δ9-THC, or butyl-THC) is a phytocannabinoid found in Cannabis that is a homologue of tetrahydrocannabinol (THC), the main active component of Cannabis."[16] "THCB has rarely been isolated from cannabis samples, but appears to be less commonly present than THC or THCV."[16] Keep this in mind, because as I cited above in a previous paragraph from the National Library Of Medicine, these products are being manufactured from CBD, not "extracted" or "isolated" from hemp. Researchers have isolated some of these cannabinoids like THC-B from Cannabis, but they exist in such small quantities that it is not profitable to isolate them for sale, so they are manufactured from CBD instead.[x] The butyl homologues of Delta9-tetrahydrocannabinol, Delta9-tetrahydrocannabutol (Delta9-THCB), and cannabidiol, cannabidibutol (CBDB), were isolated from a medicinal Cannabis sativa variety (FM2) inflorescence.[17] Some pharmacology related facts on THC-B: "The butyl homologue of Delta-9-THC, Delta-9-THCB, showed an affinity for the human CB1 (Ki = 15 nM) and CB2 receptors (Ki = 51 nM) comparable to that of (-)-trans-Delta-9-THC.[17] The results from my previously cited academic source also shows that Delta-9-THCB demonstrates a partial agonistic activity toward the CB1 receptor.[17] Here's another medical research vendor selling these rc's(research chemicals) online: https://www.caymanchem.com/product/30303/delta8-thcb It has not always been easy finding any authoritative information on some of these cannabinoids, and the question of whether or not a lot of them can even be called "cannabinoids" comes into play... The reason being that if they're synthetic, then it is more appropriate to call them pharmaceuticals, as to me a Cannabinoid is a natural God-made medicine found naturally in dried and live plant material of Cannabis.
THC- JD(): O.G. Observations: There isn't a whole lot of people even talking about these Cannabinoids online! This gives me great joy because I will gladly put these facts out there, as I love spreading what I see as important information that isn't mainstream enough. "THC-JD is a semi-synthetic cannabinoid with an eight-carbon C3 side chain, present in only trace amounts in hemp, requiring synthesis for commercial use."[19] This means that if you purchase THC-JD online, you're not buying some fancy professional extracted version, you're buying a synthetic version. There's just not enough of it in the plant to extract, sell, and profit. The practice of re-creating natural drugs artificially(like making thc from CBD), is a common modern practice in the pharmaceutical industry, as it is more cost effective, allowing the supplier to profit rather than to go out of business.. I'm about to quote and cite something that should concern you.. I suspect that someone out there may be adding old research chemicals like jwh-018 to these and labeling them anything that they want.. "To inform regulatory efforts and consumer awareness, and to address these discrepancies, this study chemically analyzed five U.S. commercial cannabis vape products marketed as containing THC-JD. Utilizing GC-MS analysis with a Δ⁸-THC-JD reference standard, no THC-JD was detected in any of the five commercial samples."[19] What was in the product then? Cops and DEA aren't going around randomly testing these products, and most of the ones on the shelves or sold online avoid being tested with a kit to determine what actual substances are in them, so it would not be hard at all to slip in anything really, including the original jwh-018 and related synthetic cannabinoids from the "k2" and "spice" era. These drugs haven't disappeared, and where there is a drug, there is a need for the holder to get rid of it. With this in mind, we can see a real danger of a market that is generally un-safe. I've tried a lot of the products on the new hemp market, and over the span of a couple of years, I've come to the conclusion that the entire market and the products sold in this new industry are generally not safe for America as a whole, as the products cause everything from brain fog(proplyene glycol[not tested for by labs]), to rotten teeth, and can even cause ulcers to bleed, due to contaminants and added poisons(not tested for). The study that I've cited in this paragraph goes on to tell us what was actually in those sampled products: "Instead, the most prevalent compound in four of the five samples was Δ⁸-THC."[19] The manufacturer lied, and tried to sell up their product by claiming that it was far more potent than it was, and really it was just delta-8 the whole time. This is why growing your own God-made narcotic ethnobotanicals is a far safer option than legal thc products made in a lab by chemist. Cannabis(Marijuana) prohibition is the real threat to America and the global population, not Marijuana itself.
THC-X: As of September 9, 2025, while I write this blog, I am unable to find an academic information on "THC-X". It hasn't shown up for any NIH listings, nor does it even have a wikipedia page or PubChem entry. Some vendors and bloggers online claim that "THC-X" is synthetic, and made from esters of other synthetic cannabinoids. THC-X is a true research chemical, or "research chemical concoction" perhaps, as I can find no academic studies on it, what-so-ever, so no one knows what it does to the human body, mind, or our cannabinoid receptor system, or even what it is.. There's no authoritative source that even tells us what the scientific name for "THC-X" is..
HHC-P: I'll work on this blog more tomorrow and later today. https://en.wikipedia.org/wiki/Hexahydrocannabiphorol
Delta-11-THC: https://en.wikipedia.org/wiki/%CE%9411-Tetrahydrocannabinol
Abeo-HHC acetate: Abeo-HHC acetate is a semi-synthetic derivative of tetrahydrocannabinol, first described in the 1980s.[33][34] It is synthesised(manufactured) from delta-11-tetrahydrocannabinol.[33][34] This means chemicals are used to produce or synthesize the drug, which right away makes the end product more dangerous than using the actual real Marijuana plant to get high.
Cis-THC(cis-Delta-9-Tetrahydrocannabinol) A.K.A.: ((-)-cis-Δ9-THC) cis-Delta-9-Tetrahydrocannabinol ((-)-cis-Δ9-THC) is an isomer of tetrahydrocannabinol found in the Cannabis plant in lesser quantities than regular THC.[35] Manufacturing of cis-THC is possible through a process of epimerization associated with acid-catalyzed cyclization of CBD to THC.[35] Here's Caymanchem again with the stock: https://www.caymanchem.com Product: cis-delta9-thc The big question is: Is Cis-THC a research chemical(synthetic/man-made), OR, is it a synthetically(artificially[man-made]) produced version of a naturally occuring cannabinoid? "While Δ9-cis-THC occurs in cannabis fiber hemp in the concentration range of (-)-Δ9-trans-THC [(-)-1], it was undetectable in a sample of high-THC-containing medicinal cannabis."[36] This means that any Cis-THC found in products on the market is being synthetically produced. Don't be confused, these products are not "extracted from hemp". The CBD is extracted, and then it is chemically synthesized(manufactured) into various forms of THC. These are hemp derived research chemicals basically. They're research chemicals because we don't know how these compounds affect the body in these large dosages that are otherwise unattainable by natural means.
Δ-3-Tetrahydrocannabinol Delta-3-thc products are available for sale online everywhere. Here is a quick example of a seller: https://www.d8austin.com/delta-3-thc-delta-6a10a-thc Delta-3-THC was developed(invented) during the original period of research in the 1940s to develop synthetic routes to the natural products Δ8-THC and Δ9-THC found in Cannabis.[37][38] That last fact is a huge deal because it illustrates that dating back to a time when slithery LSD research was taking place, there was also a slithery Cannabis related pharmaceutical agenda going on behind closed doors, and it just happens to be around the time that Cannabis prohibition was first enacted in the U.S.A... All of this has been happening right under everyones noses all these decades too. I'll update this with a better source once available but according to Wikipedia Delta-3-thc is the same as: Delta-6a10a-THC. I've seen 3chi.com selling "Delta-6a10a-THC". I don't trust 3chi. I've never gotten real "brain fog" from using illegal Marijuana, but I have from "hemp derived thc products". 3chi told me over the phone that "thc causes brain fog", and that is a lie. THC does NOT cause brain fog, if by THC you mean illegal Marijuana that hasn't been laced or tainted in some way with anything toxic. Tokers in the Cannabis community on a global scale are aware of the fact that illegal Cannabis does NOT come with the same dangers as legal Cannabis products do. An herb isn't made with chemicals, but this new wave of "hemp derived" products, are. There are rare items out there which are solventless, but most of the new "hemp" market is more like a "chemical industry", and less like a "hemp industry".
Δ-4-Tetrahydrocannabinol: Δ4-Tetrahydrocannabinol (Delta-4-THC, Δ4-THC, Δ6a(7)-THC) is a synthetic isomer of regular THC, first manufactured in the 1970s during research intended to engineer improved synthetic routes to the natural forms Δ8-THC and Δ9-THC.[39][40][41] Again, this implies that the agenda to push pharmaceutical Cannabinoids on America and the world is nothing new. This agenda includes the goal of replacing God-made ethnobotanical narcotics with pharmaceutical versions, among other things. When we look at this, and what happened with LSD in the early 1900's, and then the research chemical boom in the late 2000's(which centered around making fake synthetic versions of naturally recurring psychedelic compounds naturally produced by plants), we can see this slithery serpent medical agenda unfolding behind the scenes. I expose this and more on another blog: Exposing the slithery LSD/pharmakeia agenda connected to witches which began in the early 1900's. There's tons of authoritative academic sources on that blog to confirm everything I've just stated in this paragraph as well. I managed to find an academic source that actually tells how it is synthesized. "Alkylation of olivetol with p-menth-4-en-3,8-diol (3) afforded Delta-4-tetrahydrocannabinol, an unknown isomer of the hashish active constituent Delta-1-THC, together with the "abnormal" isomer.[42] There's very little information out there on this cannabinoid.
Δ-7-Tetrahydrocannabinol
Δ-10-Tetrahydrocannabinol
Hexahydrocannabinol
Iso-THC: Something very bizarre is going on. I found a PubChem page on Google for Delta4_8_-iso-THC, but when you click it, PubChem shows a 404 error, "Page Not Found". Here is the google search: Google search for "Delta4_8-iso-thc", and here's the broken PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/Delta4_8_-iso-THC I went to pull it up on the internet archives and nothing shows up. I don't know what to make of this as I expected it to show up on the internet archives. It's beyond suspecious, that's for sure. The fact that it shows up on Google though, indicates to me that a page did exist at one time. We have a couple pieces of proof that it is in fact a real academicly confirmable chemical, as it is showing up in scholarly journals, and I cite a source at the end of this sentence to prove that.[44] This to me makes it look like things are being hidden, and reminds me of the time the CDC removed a page on prescription drug deaths that I was linking to from my old operation called BotanicalGuides.com. The second piece of proof that this is a real compound is in the fact that research chemical vendors online have variations of Iso-THC available for registered medical research facilities(labs): https://www.caymanchem.com/product/33864/delta8-iso-thc These labs have DEA licensing which allows them access to controlled substances for scientific research purposes. The more you learn about the research into these compounds, and the large number of not-natural(man-made) cannabinoids that exist, the true workings of serpent medical start to become apparent. Modern medical science has a sneaky slithery way of operating behind the scenes, and their publications are policed, not advertised, by agencies(FDA, etc), and occult gangs(secret societies like the wiccans, nazi's(odin brotherhood, skull and bones), freemasons(eastern star, etc), satanic temple related cults, etc) If that sounds crazy to you then I have a full blog with academic sources and citations that fully proves the occult connection to the modern pharmaceutical industry. This reminds me of the words of John F Kennedy just prior to his assasination: "The very word secrecy is repugnant in a free and open society. and we are as a people, inherently and historically opposed to secret societies, to secret oaths, and to secret proceedings. We decided long ago, that the dangers of excessive and unwarranted concealment of pertinant facts, far outweighed the dangers which are cited to justify it."[43] He's speaking about disclosing facts to illustrate innocence and hard work being done by the government for the people. This is to show that nothing sinister is taking place behind the scenes. Disclosure is a good thing. However, when it comes to the inventions of LSD, JWH-018, Delta8THC and others, these operations were not advertised, publicly disclosed, or anything of the like. They were done quietly behind closed doors in guarded secrecy, masked with cover stories like "bicycle day". The truth is buried in the academic sources, books, etc, and upon investigation, one can see that which is hidden in plain sight. The best example to illustrate what I am talking about is how Albert hofmann's own books reveal the truth, yet in public and on documentaries he lies and covers the truth with a story called "bicycle day"[https://www.npr.org/2024/04/19/1245810413/bicycle-day-marks-an-unofficial-commemoration-of-the-first-use-of-lsd], which totally contradicts his own writing, and academic facts related to his field and the academic knowledge and discovery of natural lysergic alkaloids far before his invention of LSD.. The medical establishment conceals more than it reveals.
Cycloheptyl CP 55,940: Cycloheptyl CP 55,940 is a synthetic cannabinoid related to CP 55,940 that was first synthesized(engineered) by Pfizer(a pharmaceutical company) in the 1980s.[45][46] Let's see if the PubChem page is live on this one, because for the last compound it was missing, and displayed "page not found". https://pubchem.ncbi.nlm.nih.gov/compound/cp55940 It looks like this cannabinoid is listed on PubChem and the page is live. I will archive the url now to be a patriot, with the internet archive save tool. Again, we can see CaymanChem supplying this one as well: https://www.caymanchem.com/product/13241/%28%C2%B1%29-cp-55%2C940, to research labs that have DEA licensing, etc. Cayman Chem isn't the only research chemical vendor that supplies research labs with these drugs, by the way. I've found another scholarly source that confirms for us that Pfizer is a pharmaceutical company that has been making and experimenting with cannabinoids for some time now, including CP 55,940.[47] According to an academic source that I cite via the Journal Of Biological Chemistry: "During a search for novel drugs possessing analgesic properties but devoid of the psychotropic effects of marijuana, a group of molecules designated as nonclassical cannabinoids was synthesized by Pfizer. Of these nonclassical cannabinoids CP-55,940 has received the most attention principally because it was used as the high affinity radiology and during the discovery and characterization of the G-protein-coupled cannabinoid receptor."[47] Keep in mind the word "synthesized" is a nice way of saying "manufactured". By the way the date at the top of the source I just cited is May 3, 1996. According to Merriam-Webster's Dictionary, Synthesize means to : " 1. : to combine or produce by synthesis. : to make a synthesis of. 3. : to produce something"(https://www.merriam-webster.com/dictionary/synthesize)
CP 47,497
O-1656 "O-1656 is a cannabinoid agonist which was invented by Billy R Martin and Raj K Razdan at Organix Inc in 2002. It is moderately selective for the CB2 receptor with a CB1 receptor affinity of 18 nM and a CB2 receptor affinity of 2 nM."[49][50][51][48] Here is the wiki for Organix Inc: https://en.wikipedia.org/wiki/Organix_Inc and I found a website: https://organixinc.com/ The title says "Organix: Custom Synthesis, Research Chemicals & Services". Their website states that: "To support researchers, we offer a growing selection of non-proprietary compounds, including standards, building blocks, and intermediates. Available classes include lipids, maleimides, and more. As a DEA-licensed company (Schedules I–IV), we are able to conduct research and manufacture controlled substances. Furthermore, we can develop medicinal chemistry libraries of scheduled compounds."(via: organixinc.com) It goes on to state that: "At Organix, we specialize in small-molecule chemistry, bringing elegant solutions to complex challenges. With our off-the-shelf offerings including lipids for use in lipid nanoparticles (LNPs), GalNAc conjugates, oligonucleotide-related products, and water-soluble polymer conjugates, we provide a wide variety of high-quality chemical compounds tailored to your needs."(via: organixinc.com) I called them up to ask them about the cannabinoid: 0-1656 but when they asked me which company or institution I was with and I explained that I'm just a blogger exposing how big pharma is making cannabinoids, they were hesitant, put me on hold, basically didn't answer the question, and told me to send them an email explaining all of this. It's like me asking questions made them nervous.
THC-O-acetate
Abn-CBD
CBD-DMH
Exo-THC
HU-211
Perrottetinene
Machaeriol A
7,8-Dihydrocannabinol
Cannabitriol
JWH-138
Parahexyl
L-759,656 L-759,656 is a cannabinoid that has analgesic effects and is a cannabinoid agonist.[21] It is a highly selective agonist for the CB2 receptor, with selectivity of 414x for CB2 over CB1.[21] The first thing I notice when searching for this Cannabinoid "L-759,656" in the scholarly databases, is that the first page of results that comes up shows it listed next to JWH133 and related synthetic cannabinoids from back in the late 2000's, from the "k2" and "spice" days.. This makes me think it's an older Cannabinoid, and not naturally occuring. It also tells me that there has been an insane amount of medical research into the pharmacology of synthetic man-made cannabinoids. This truly illustrates that leading up to the legalization of hemp, this was all pre-planned. The new hemp industry is more about a grey area loop-hole that allows chemist to create research chemical versions of THC from CBD derived from Hemp. It looks as though it has been in the works for a long time. Further evidence of a slithery serpent agenda to make fake versions of God-made narcotic ethnobotanicals such as Cannabis, is LSD. I wrote a full blog on this. LSD was the first research chemical that I am aware of, as it is a pharmaceutical version of a series of naturally recurring ergot alkaloids found in nature. All of the various natural sources for ergot have been connected to the occult in some way, and are primarily tied to the practices of divination and necromancy, as well as pagan worship(ceremonies, ritual, practice, etc).
More On L-759,656: To show that there has been scientific research on synthetic cannabinoids(one's that don't exist naturally in Cannabis), I am quoting any academic journal titled "Primary Macrophage Chemotaxis Induced by Cannabinoid Receptor 2 Agonists Occurs Independently of the CB2 Receptor". The source states: "Activation of CB2 has been demonstrated to induce directed immune cell migration. However, the ability of CB2 to act as a chemoattractant receptor in macrophages remains largely unexplored. Using a real-time chemotaxis assay and a panel of chemically diverse and widely used CB2 agonists, we set out to examine whether CB2 modulates primary murine macrophage chemotaxis. We report that of 12 agonists tested, only JWH133, HU308, L-759,656 and L-759,633 acted as macrophage chemoattractants. Surprisingly, neither pharmacological inhibition nor genetic ablation of CB2 had any effect on CB2 agonist-induced macrophage chemotaxis. As chemotaxis was pertussis toxin sensitive in both WT and CB2-/- macrophages, we concluded that a non-CB1/CB2, Gi/o-coupled GPCR must be responsible for CB2 agonist-induced macrophage migration. The obvious candidate receptors GPR18 and GPR55 could not mediate JWH133 or HU308-induced cytoskeletal rearrangement or JWH133-induced β-arrestin recruitment in cells transfected with either receptor, demonstrating that neither are the unidentified GPCR. Taken together our results conclusively demonstrate that CB2 is not a chemoattractant receptor for murine macrophages. Furthermore we show for the first time that JWH133, HU308, L-759,656 and L-759,633 have off-target effects of functional consequence in primary cells and we believe that our findings have wide ranging implications for the entire cannabinoid field."[20] The source that I just quoted and cited also proves that JWH-018 and the original synthetic cannabinoids were an academic operation, and that they have been studied for their medicinal value(pharmacology) in academic settings. Furthermore, this backs up what I was saying about Bouncing Bear Botanicals being an academic operation. The ethnobotanical industry is tied in with academia. O.G. Observation: It is heavily policed by secret societies, and the occult, and even the DEA, and police(as these groups hide within the agencies so they can steal drugs to fund illegal prostitution operations with: https://www.nbcnews.com/news/us-news/dea-agents-held-sex-parties-linked-drug-cartels-report-n330641) I'm a third eye witness. I was there.
Remember, all of this "legal thc" began with "spice", and "k2", which was birthed from academia and medical research. It's important to know that the original synthetic cannabinoids found in "spice" and "k2" (ie: "herbal incense"), still exist, and are still being manufactured and sold, both legally and illegally, and even disguised as "legal hemp derived" products. You never know what's in any of these legal products, period. It's a highly dangerous market. Get real non-gmo Marijuana seeds here and do things Gods way: HerbiesHeadShop.com They ship to the USA. Avoid "thca seeds" and "thca flower", as it is genetically engineered(gmo)[Self evident]. All tokers of illegal cannabis over the decades can tell the difference between that "thca" crap, and real bud. Don't let the socialist gaslight you.
JWH-Series Of Research Chemicals: For those of you who don't know, weren't there, or don't remember, back in the late 2000's there was a "spice", or "k2" boom, and it was also called "herbal incense". What these products were, was herbs of any kind, laced with synthetic cannabinoid, and then marketed as an "incense"(wink wink). They were sold in smoke shops and gas stations across the U.S. until they were banned. The chemcials in these blends that made them active originate from academic sources. I thoroughly prove that on this blog because I just cited a source in the previous paragraph above that mentions some of these original synthetic cannabinoids, and they have been studied for their pharmacology. That means we know their benefits, and even their harmful effects. Back in the day, LegalHighGuides.com was a place where people sold, swapped, traded, shared, and sampled out tons of research chemcials and "herbal incense" blends. There was a huge booming legal industry, and it was academics and those involved in medical research who were behind this booming market. In other words, these drugs were coming from people in high places, not the trailer park.
Important facts: "JWH-018 (1-pentyl-3-(1-naphthoyl)indole), one of the first novel psychoactive substances detected in a "Spice" product by forensic investigators in Germany and Austria in 2008, was created as part of a research program led by Dr. John Huffman at Clemson University, Clemson, South Carolina (Emcdda, 2017, Wiley et al., 2014)."[26]
Below is an embedded news story about a self made millionaire from Kansas(the owners of Bouncing Bear Botanicals) who was involved with an international side operation of "k2" manufacturing and distribution back up until around 2011-2012. Him and the fam were making jwh-018 and other synthetic cannabinoids, as they're academics and because of the research going on at the time, these were legal, so they took advantage and capitolized on it with their invention of "k2"(herbal incense). Bouncing Bear Botanicals was as much of an academic operation as it was a financial one. His documentary "footprints of the shaman" stared many scholars including Dennis Mckenna[https://en.wikipedia.org/wiki/Dennis_McKenna] I've proven with my sources on this blog that these research chemicals are in fact an academic/pharmaceutical operation. These types of drugs are not coming from the trailer park. The big dawgs are getting protection from the five pointed star that the police wear(government backing.) They're in the police departments, DEA, FBI, etc. To prevent any confusion, Bouncing Bear Botanicals didn't sell "k2" or any research chemical laced products, "k2" was being sold out of his other shop "Sacred Journey", and as a side item, which made up ~1% of his entire inventory.
JWH-018, Long name: naphthalen-1-yl-(1-pentylindol-3-yl) methanone: Here is a .mil with a photo of a package of k2 on it for those who want to see: https://www.army.mil/article/47388/spice_the_other_marijuana. It was sold back in the day under many names. Jwh-018 was the original synthetic cannabinoid that was used in these mixtures. Before I share what the academic studies show in regards to the dangers of this substance, and related JWH-substances, I want to remind everyone that these JWH-related cannabinoids are synthetic, man-made drugs, that do NOT exist naturally in Real Marijuana. This means that we can not apply our judgement on their negative impact on human health to Cannabis, because real Cannabis and fake thc made in a lab are not the same thing. You gotta keep 'em separated. One academic source on Jwh-018 states that: "In a case report (Zimmermann et al., 2009), a former regular user of hashish (a concentrated preparation of cannabis) switched to an herbal preparation containing JWH-018. After discontinuing use of the JWH-018-containing product, a severe withdrawal syndrome emerged, which was alleviated by resuming use of the herbal mixture. The subject reported the effects of JWH-018 to be stronger than hashish, but less euphoric. Recent case studies indicate that JWH-018 has effects similar to, although perhaps not identical with, those of cannabis and Delta-9-tetrahydrocannabinol (Delta-9-THC); in particular, JWH compounds seem to have effects on the cardiovascular system that are distinct from those observed after Delta-9-THC administration (Simmons et al., 2011; Young et al., 2011)."[22] By the way, JWH-018 is still manufactured, and sold(distributed) to licensed medical facilities and research facilities for research. https://www.caymanchem.com/product/10900/jwh-018?srsltid=AfmBOoo9Kallf7yM7R3a-2jeoZyw1G_O2NB5F2BrdZ5ta-0l1qnQ3OQu Call them yourself and ask them. I called them for the sake of gaining intel, and asked them and they confirmed for me, and can for you too. A woman on the phone told me she pulled up 177 results for "jwh-018". She said see the full catalog on caymanchem.com
JWH-018 Continued: Let's talk more about what the science says about JWH-018. The scientific name for JWH-018 is: naphthalen-1-yl-(1-pentylindol-3-yl) methanone.[22] The chemist the substance was named after is John W. Huffman Here's his wikipedia: https://en.wikipedia.org/wiki/John_W._Huffman "Beginning in 1984, Huffman and his team of researchers began synthesizing cannabinoid compounds with delta-9-tetrahydrocannabinol (THC) properties for medical research purposes."[23] "Over the course of twenty years, Huffman and his team developed over 400 synthetic cannabinoid compounds which were used as pharmacological tools to study endocannabinoids and cannabinoid receptor genetics. Ultimately, the cannabinoid research provided better understanding of the physiological cannabinoid control system in the human body and brain and opened a path of "elucidating this natural regulatory mechanism in health and disease."[24] This predates the "hemp derived cannabinoid industry", and suspeciously at that. What it looks like to me is that these products could be anything. There could be anything in them. I've shared enough proof via academic sources on this page in paragraphs above to confirm that already. Products like delta-8, HHC, thcp, etc, are the evolved version of this movement. While synthetic cannabinoids produced from CBD are safer on their own, the potential residual solvents left over in the manufacturing process make them ultimately less safe, and then there's the potential for the addition of other substances and chemicals to the product to make it more dangerous.
JWH Studies: According to a journal published on the National Library Of Medicine website: "In the present study the effects of acute exposure to JWH-018, JWH-018-Cl, JWH-018-Br (JWH-018-R compounds) and Δ(9)-THC (for comparison) on Novel Object Recognition test (NOR) has been investigated in mice. Moreover, to better characterize the effects of JWH-018-R compounds on memory function, in vitro electrophysiological and neurochemical studies in hippocampal preparations have been performed. JWH-018, JWH-018-Cl and JWH-018-Br dose-dependently impaired both short- and long-memory retention in mice (respectively 2 and 24 h after training session)."[25] On that note I'd like to add an O.G. Observation: When I smoked spice in the past(around 2009), it for sure had a more harmful impact on my short term memory, far worse than real Marijuana. The study goes on to state that: "Their effects resulted more potent respect to that evoked by Δ(9)-THC. Moreover, in vitro studies showed as JWH-018-R compounds negatively affected electrically evoked synaptic transmission, LTP and aminoacid (glutamate and GABA) release in hippocampal slices. Behavioral, electrophysiological and neurochemical effects were fully prevented by CB1 receptor antagonist AM251 pretreatment, suggesting a CB1 receptor involvement. These data support the hypothesis that synthetic JWH-018-R compounds, as Δ(9)-THC, impair cognitive function in mice by interfering with hippocampal synaptic transmission and memory mechanisms. This data outline the danger that the use and/or abuse of these synthetic cannabinoids may represent for the cognitive process in human consumer. "[25]
JWH Toxicity: "Unlike THC, a partial agonist, synthetic cannabinoids tend to be full agonists, or even "super agonists", at the CB1 receptor. This often results in enhanced potency compared to THC and provokes more severe side effects and health risks, including neurological effects, psychiatric episodes, arrhythmia, respiratory failure, kidney injury, and death(Manini et al., 2022)."[26] According to one study published on the National Library Of Medicine website: "In histopathological analysis, neural cells of the animals treated with the high dose (5 mg/kg) of JWH-081 or JWH-210 showed distorted nuclei and nucleus membranes in the core shell of nucleus accumbens, suggesting neurotoxicity. Our results suggest that JWH-081 and JWH-210 may be neurotoxic substances through changing neuronal cell damages, especially in the core shell part of nucleus accumbens."[27] Another academic source confirms for us that: "In agreement with human studies and case reports, this study found that synthetic cannabinoids generally produced more seizures than THC."[28] The journal previously cited goes on to state that: "It has been estimated that synthetic cannabinoids (SCs) are 30 times more likely than cannabis to result in the need for emergency medical treatment."[28] If you remember the blog I put together called: exposing-2ci-2cb-2ce-2cn-fake-mescaline-dangers-precursors.html, then you should remember how the research shows that pharmaceutical(non-natural, man-made, synthetic) versions of phenethylamines like Mescaline and Amphetamines, are far more harmful than the natural God-made versions of these substances, which are produced by ethnobotanicals(Mescaline, Amphetamines). More scientific findings on the effects of JWH-018 include: "The adolescent voluntary consumption of JWH-018 leads to long-lasting behavioral and neurochemical aberrations along with glia-mediated inflammatory responses in adult brains."[30] "The misuse of synthetic cannabinoid receptor agonists (SCRAs) poses major psychiatric risks. We previously showed that repeated exposure to the prototypical synthetic cannabinoid receptor agonists JWH-018 induces alterations in dopamine (DA) transmission, abnormalities in the emotional state, and glial cell activation in the mesocorticolimbic dopamine circuits of rats."[31] If you've ever felt like you were coming down with a cold after using any type of "I can't believe it's not weed" products("spice", "k2", "delta8", "thca flower", and all manners of other fake crap), then the following academic finding can offer you an explanation: "JWH-018 exposure induces enduring brain region-specific immune alterations, which may contribute to the behavioral and neurochemical dysregulations in striatal areas that play a role in reward and reward-related processes, such as addictive behaviors."[31] The keywords that I am bringing your attention to there are "immune alterations". Remember, the endocannabinoid system is part of our bodies immune system[32], and when it is exposed to exogenous poisons meant to mimic the effects of REAL THC(jwh-018, thcp, and other synthetics), it can have damaging and harmful effects on our immune system. According to the National Library Of Medicine: "Endocannabinoids are believed to control immune functions and play a role in immune homeostasis."[32]
JWH-133: "JWH-133 induced a concentration-dependent decrease of SH-SY5Y cell viability and proliferation rate. Using AM-630, a reverse agonist of CB2 receptors, as well as Z-VAD-FMK, a pan-caspase inhibitor, we demonstrated that the cytotoxic effect of JWH-133 presumably was not mediated by activation of CB2 receptors or by caspase pathway. Results of this work suggest that agonists of CB2 receptors when administered in multiple/high doses may induce neuronal damage."[29] This proves that pharmaceutical cannabinoids(man-made, not naturally occuring, synthetic, research chemicals) do not have the same safety profile, or miraculous nature as do the God-made versions of these substances(natural God-made THC, etc). These types of conclusions when we look at the scholarly research, are predictible patterns. The natural(God-made) versions are ALWAYS safer, but they always prohibit the God-made versions, and then push their pharma versions instead. They're telling the public that pharmaceuticals are the way, and to avoid ethnobotanicals(the God-made versions of these narcotics[like Marijuana]).
More JWH Era Research Chemicals From The "k2" Days: More synthetic cannabinoid compounds from the JWH("k2"/"spice") era include: JWH-022, JWH-122, UR-144, AM-2201, JWH-018-Cl, JWH-019, HU-210 Classic cannabinoid AM-694, RCS-4, WIN 48,098, CP-47,497, JWH-073, JWH-081, JWH-122, JWH-210, AM-2201, JWH-203, JWH-250, and RCS-8. [Here's wiki's list: https://en.wikipedia.org/wiki/Synthetic_cannabinoids] This list will evolve.
Synthetic Cannabinoids and "Herbal Incense" Are Still A Thing: If you think that something being made illegal makes it go away, think again. A simple Google search renders us insane numbers of online vendors that are STILL SELLING "herbal incense"(products laced with jwh and related original synthetic cannabinoids meant to mimic the effects of God-made THC). Look: https://www.google.com/search?hl=en&source=hp&biw=&bih=&q=buy+herbalincens Here are a few shops for further illustration: , I don't get paid for the references, as I merely link to them to illustrate that these things are still in demand, and are being sold online: https://www.herbalincence.com/, https://www.onlineherbalincense.com/, https://www.herbalincensepremium.com/, https://buy-herbal-incense.company.site/, https://www.expresshighs.com/herbal-incense?limit=100, https://www.usaincense.com/, https://herbalincenseempire.com/shop/, https://k2spiceshop.com/product/herbal-incense-diablo/ Just for good intel, I reached out to each vendor to see if they would ship it to Florida(an illegal act), and look what they said(they said yes): USAIncense.com agrees to ship spice to Florida(screenshot1), and: USAIncense.com email address confirmation screenshot #2. Here is HerbalIncense.com admitting they will ship spice to Florida(which is illegal): HerbalIncense.com illegally ships spice to Florida, admits it in WhatsApp
THCA Flower is NOT "real weed" This is the big socialist lie that's swarming the internet. All seasoned smokers who have toked on real illegal Marijuana their entire life, can tell that "thca flower" is NOT the same marijuana as the illegal Marijuana. Logic and intel would indicate that it is genetically engineered, and it is an un-Godly, un-natural, altered abomination. I have embedded a video below that details "HOW TO MAKE THCA FLOWER"
Ethnobotany: What is Ethnobotany? According to Stetson University, Ethnobotany is defined as: "The study of the practical uses of plants within a particular region or culture, focusing on traditional knowledge and customs regarding medicinal, religious, and other applications."(Via: Stetson.EDU) Ethnobotany has major biblical, cultural, and industrial implications. It's a pre-requisit to phytochemistry, as the two fields of study are closely related to one another and co-dependent.
What is Phytochemistry? It has everything to do with the Cannabinoids being discussed on this blog, as well as the study of naturally occuring medicines in general. Phytochemistry is defined as: "Phytochemistry is the study of the chemistry of substances found in plants."(Via: https://ibs.upm.edu.my/content/phytochemistry-34443) See also: https://phytochem.nal.usda.gov/
Phytochemicals: What are Phytochemicals? Phytochemicals are miraculous drugs and medicines produced by plants(ethnobotanicals).[1][2][3][4] They are studied in the laboratory for their complex medicinal properties.[1][2][3][4] If you're still confused about what a phytochemical is, please see my blog titled: difference-between-research-chemicals-and-phytochemicals.html
Important Related Educational Blogs: Exposing The Occult Socialist Plot Against The Original Ethnobotanical Industry And Why It Matters.,Exposing the '2c series' of research chemicals as fake mescaline and fake amphetamines.,Whats the difference between natural DMT and research chemical DMT?,Quiz One On DMT,Natural Amphetamines Vs Research Chemical Amphetamines,,Whats the difference between research chemicals and phytochemicals?,Medical(Pharmacology Glossary),,Quiz One On Mind Body Systems,Quiz 1 on: Marijuana Prohibition & Socialist Propaganda During 1900's, Astrophytum myriostigma cactus(Bishops Cap) Produces Mescaline, Exposing Freemasonry's Satanic Occult Roots, Connection To Genocide, 911, and Porn/Prostitution., History Of Marijuana Prohibition In America, and Why It Matters, What Happened To Arena Ethnobotanicals?, What Happened To BotanicalSpirit.com Ethnobotanical Shop?, What Happened To Bouncing Bear Botanicals?, What happened to Edens Ethnobotanicals?, What happened to Meridian Botanicals?, What Happened To MR. Botanicals?, Exposing Crimes Of The Pensacola FBI, DEA, and SRCSO., Corrupt Ethnobotanical Industry Exposed, Occult Crime Rings., Exposing Modern Medicines Connection To The Occult, Exposing Deadly Hallucinogenic Plants Utilized By Big Pharma Companies That's Tied To Witchcraft(Bella Donna & scopolamine), Exposing pirates, skull and bones(nazi's), and their connection to each other, and the occult(which is tied to ethnobotanicals), Exposing Witchcraft and its intentions, Exposing Legal FAKE "magic mushroom" Gummies Laced With Poison And Possibly Research Chemicals, Tabernanthe Iboga. produces Ibogaine, an illegal medicine/psychedelic., LEGAL PLANT PRODUCES TREMADOL!, Covid19 Vaccine Dangers Exposed Via Academic Sources!, Exposing Asatrue Alliance, Nazi/Occult Hate Group, Exposing Skull And Bones, A Satanic Nazi Cult Tied To The OCCULT and POISONOUS PLANTS, Exposing The Odin Brotherhood, A Nazi Gang Tied To The Plot AGainst Edens Ethnobotanicals, Genocide, and the Oklahoma City Bombing(as well as the Pensacola FBI, DEA, and SRCSO and illegal prostitution/cyber crime!), Exposing The Occult Origins Of LSD and Research Chemicals, Pharma Wants To Rob America Of Natural Ibogaine And Replace With Pill Version, Legal Plants That Produce Illegal DMT, Plants That Produce Ketamine
Ethnobotanical/Drug/Critical News: BBC Documentary Exposes Nazi Connection To Oklahoma City Bombing, Larry Silverstein On PBS Admitting Building 7 Was "Pulled", A Term Used In Controlled Demolitions, Unsolved Mysteries Episode Exposing Satanic Cults Stealing And Stocking GUNS, AlJazeera News: UK Authorities Seize Over 2 TONNES Of Cocaine In One Of The Largest Busts In History!, Record Cocaine Bust In UK London PORT!, FBI RAID: Enough Fentanyl To Kill Georgia's Population 4 TIMES!, Pam Bondi Announces Largest Fentanyl Bust In US History, Southcom.MIL Coast Guard Offloads 265 Tons OF Cocaine Seized In Eastern Pacific Drug Transit, Justice.gov Attorney General Pam Bondi: DEA In New Mexico Announces Historic Drug Bust!, Mass.gov Sixteen Charged After Takedown Of Major Fentanyl And Cocaine Trafficking Operation In South Eastern Massachusetts, Vice: Multi-Million Dollar Illegal MDMA/LSD Manufacturing Operations EXPOSED, Largest Bust In Canadian History! Superlab Producing Methamphetamines and Fentanyl, as well as precursors!(International operation), Justice.gov Two Indian Chemical Companies And Senior Executive Indicted For Distribution Of Fentanyl Precursors, Justice.gov Largest Fentanyl Bust In DEA History, Over 400 Kilos Of Fentanyl Seized!, CNN South African Police Uncover Multi-Million Dollar Meth Lab On Farm Being Run BY ALL SKIN COLORS!, CBS NEWS: New Pacific Drug Trafficking Route Narco Subs Uncovered! | Exposing LSD Precursors Legally Sold By Ethnobotanical Industry, Sassafras, Safrole, MDA, Camphor, Precursors Used In Illegal MDMA Manufacturing Operations, New DOJ watchdog report details FBI officials' misconduct with foreign prostitutes, justice.gov: Investigative Summary: Findings of Misconduct by a then-Federal Bureau of Investigation Supervisory Special Agent for Solicitation and Use of Prostitutes While on FBI Assignment Overseas and Traveling Domestically, Failure to Self-Report Close or Continuous Contacts with Foreign Nationals, and Related Misconduct, FBI officials had sex with prostitutes while overseas, inspector general investigation finds., NBCNEWS: Dea Agents Held Sex Parties With Prostitutes Linked To Drug Cartels, , https://www.cbsnews.com/news/government-report-dea-agents-had-sex-parties-with-prostitutes/, Pensacola brothers in antisemitic vandalism spree get probation, https://www.wuwf.org/local-news/2023-03-29/pensacola-rally-calls-for-unity-against-neo-nazis-and-white-supremacists
Academic citations:
[1] National Library Of Medicine: Dietary Phytochemicals in Health and Disease: Mechanisms, Clinical Evidence, and Applications—A Comprehensive Review | https://pmc.ncbi.nlm.nih.gov/articles/PMC11922683/ | PMCID: PMC11922683 PMID: 40115248
[5] (-)- trans-Δ9-Tetrahydrocannabiphorol Content of Cannabis sativa Inflorescence from Various Chemotypes | https://pubmed.ncbi.nlm.nih.gov/33565878/ | PMID: 33565878 DOI: 10.1021/acs.jnatprod.0c01034
[6] CBD, a precursor of THC in e-cigarettes https://pubmed.ncbi.nlm.nih.gov/33903673/ PMID: 33903673 PMCID: PMC8076212 DOI: 10.1038/s41598-021-88389-z
[8] University Of San Francisco: https://myusf.usfca.edu/environmental-health-safety/controlled-substance-precursor-chemical-program
[9] 5 Things to Know About Delta-8 Tetrahydrocannabinol: Delta-8 THC | PMCID: PMC9312454 PMID: 36033151 | https://pmc.ncbi.nlm.nih.gov/articles/PMC9312454/
[10] Benowitz, Neal L., et al. "Vaping THC-O acetate: potential for another EVALI epidemic." Journal of Medical Toxicology 19.1 (2023): 37-39.
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[12] Starks M (1990). Marijuana Chemistry: Genetics, Processing, Potency. Ronin Publishing. ISBN 978-0-9141-7139-3.
[13] Holt, Alaina K., Justin L. Poklis, and Michelle R. Peace. "∆ 8-THC, THC-O acetates and CBD-di-O acetate: emerging synthetic cannabinoids found in commercially sold plant material and gummy edibles." Journal of Analytical Toxicology 46.8 (2022): 940-948. https://pubmed.ncbi.nlm.nih.gov/35674405/ https://academic.oup.com/jat/article/46/8/940/6604286
[14] Virginia Commonwealth University: https://scholarscompass.vcu.edu/frsc_projects/84/
[15] https://health.mo.gov/safety/cannabis/pdf/hemp-derived-cannabinoids.pdf
[16] Linciano P, Citti C, Luongo L, Belardo C, Maione S, Vandelli MA, et al. (January 2020). "Isolation of a High-Affinity Cannabinoid for the Human CB1 Receptor from a Medicinal Cannabis sativa Variety: Δ9-Tetrahydrocannabutol, the Butyl Homologue of Δ9-Tetrahydrocannabinol". Journal of Natural Products. 83 (1): 88–98. doi:10.1021/acs.jnatprod.9b00876. hdl:11380/1190198. PMID 31891265. S2CID 209519659.
[17] Linciano, Pasquale, et al. "Isolation of a high-affinity cannabinoid for the human CB1 receptor from a medicinal Cannabis sativa variety: Δ9-tetrahydrocannabutol, the butyl homologue of Δ9-tetrahydrocannabinol." Journal of natural products 83.1 (2019): 88-98.
[18] PubChem Delta-9-THCB: https://pubchem.ncbi.nlm.nih.gov/compound/trans-delta-9-Tetrahydrocannabutol
[19] Munger, K., Bone, C., Anreise, K., & Strongin, R. (2025). Analysis of Novel Cannabis Products Labeled as Containing THC-JD.
[20] Taylor, L., Christou, I., Kapellos, T. S., Buchan, A., Brodermann, M. H., Gianella-Borradori, M., ... & Greaves, D. R. (2015). Primary macrophage chemotaxis induced by cannabinoid receptor 2 agonists occurs independently of the CB2 receptor. Scientific reports, 5(1), 10682.
[21] Ross RA, Brockie HC, Stevenson LA, Murphy VL, Templeton F, Makriyannis A, Pertwee RG (February 1999). "Agonist-inverse agonist characterization at CB1 and CB2 cannabinoid receptors of L759633, L759656, and AM630". British Journal of Pharmacology. 126 (3): 665–72. doi:10.1038/sj.bjp.0702351. PMC 1565857. PMID 10188977.
[23] Terrence McCoy. How this chemist unwittingly helped spawn the synthetic drug industry, The Washington Post, August 9, 2015.
[24] Onaivi, Emmanuel S., et al. Endocannabinoids and cannabinoid receptor genetics, Progress in Neurobiology, Volume 66, Issue 5, April 2002, Pages 307-344.
[25] Barbieri, M., Ossato, A., Canazza, I., Trapella, C., Borelli, A. C., Beggiato, S., ... & Marti, M. (2016). Synthetic cannabinoid JWH-018 and its halogenated derivatives JWH-018-Cl and JWH-018-Br impair Novel Object Recognition in mice: Behavioral, electrophysiological and neurochemical evidence. Neuropharmacology, 109, 254-269. https://pubmed.ncbi.nlm.nih.gov/27346209/
[26] Fenghua Zhou, Yan Shi, Sujun Tan, Xiaoli Wang, Weicheng Yuan, Shuqi Tao, Ping Xiang, Bin Cong, Chunling Ma, Di Wen, Unveiling the toxicity of JWH-018 and JWH-019: Insights from behavioral and molecular studies in vivo and vitro, Ecotoxicology and Environmental Safety, Volume 289, 2025, 117500, ISSN 0147-6513, https://doi.org/10.1016/j.ecoenv.2024.117500. (https://www.sciencedirect.com/science/article/pii/S0147651324015768)
[27] Cha, H. J., Seong, Y. H., Song, M. J., Jeong, H. S., Shin, J., Yun, J., ... & Kim, H. S. (2015). Neurotoxicity of synthetic cannabinoids JWH-081 and JWH-210. Biomolecules & Therapeutics, 23(6), 597. https://pmc.ncbi.nlm.nih.gov/articles/PMC4624077/
[28] Breivogel, C. S., Wells, J. R., Jonas, A., Mistry, A. H., Gravley, M. L., Patel, R. M., ... & Brenseke, B. M. (2020). Comparison of the neurotoxic and seizure-inducing effects of synthetic and endogenous cannabinoids with Δ9-tetrahydrocannabinol. Cannabis and cannabinoid research, 5(1), 32-41.
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Encyclopedia Sources:
[38] https://en.wikipedia.org/wiki/Δ3-Tetrahydrocannabinol
[48] 0-1656: https://en.wikipedia.org/wiki/O-1656
JWH-018: https://en.wikipedia.org/wiki/JWH-018
11-Hydroxy-THC: https://en.wikipedia.org/wiki/11-Hydroxy-THC
THCB: https://en.wikipedia.org/wiki/Tetrahydrocannabutol
https://en.wikipedia.org/wiki/%CE%9411-Tetrahydrocannabinol
https://en.wikipedia.org/wiki/%CE%9411-Tetrahydrocannabinol
https://en.wikipedia.org/wiki/Abeo-HHC_acetate
https://en.wikipedia.org/wiki/Cis-THC
https://en.wikipedia.org/wiki/%CE%94-3-Tetrahydrocannabinol
[41] https://en.wikipedia.org/wiki/%CE%94-4-Tetrahydrocannabinol
https://en.wikipedia.org/wiki/%CE%94-7-Tetrahydrocannabinol
https://en.wikipedia.org/wiki/%CE%94-10-Tetrahydrocannabinol
https://en.wikipedia.org/wiki/Iso-THC
https://en.wikipedia.org/wiki/L-759,656
https://en.wikipedia.org/wiki/Tetrahydrocannabutol
Documentaries:
Bouncing Bear Botanicals Films: Footprints Of The Shaman
Other resources:
M.A.P.S. Ethnobotanical Studies By Scholars
National Library Of Medicine https://www.nlm.nih.gov/
PubChem - pubchem.ncbi.nlm.nih.gov